AstraZeneca (AZN) is a global biopharmaceutical powerhouse, headquartered in the UK and listed on the NASDAQ as an ADR. The company is known for its leadership in oncology, cardiovascular, renal, respiratory, and immunology therapies. Through a strong R&D pipeline and targeted acquisitions, AstraZeneca has evolved into one of the most cash-generative pharma companies globally.
Financial Performance (2023 – 2025)
| Key Indicator | 2023 | 2024 | 2025 | Trend |
|---|---|---|---|---|
| Revenue | $45.99B | $54.10B | $58.12B | +26% |
| Operating Income | $9.45B | $12.79B | $12.72B | +35% |
| Net Income | $5.98B | $7.04B | $9.41B | +57% |
| EPS (Diluted) | $1.91 | $2.25 | $3.01 | +57% |
| Free Cash Flow | $9.31B | $10.28B | $12.97B | +39% |
- Strong double-digit revenue growth driven by oncology and immunology.
- Net income and EPS surging thanks to margin expansion and lower exceptional charges.
- FCF at an all-time high, giving AstraZeneca flexibility in dividends and R&D.
Margins: Premium Pharma Efficiency
| Margin Type | 2023 | 2024 | 2025 | Comment |
|---|---|---|---|---|
| Gross Margin | 73.95% | 74.98% | 73.25% | Top-tier pharma |
| Operating Margin | 20.54% | 23.65% | 21.89% | Robust expansion |
| Net Profit Margin | 13.00% | 13.01% | 16.19% | 💪 Trending higher |
💡 AstraZeneca’s margins rival those of much larger firms — and its net margin improvement reflects successful cost control amid higher R&D.
Cash Flow & Capital Allocation
| Cash Flow Items | 2023 | 2024 | TTM 2025 | Comment |
|---|---|---|---|---|
| Operating Cash Flow | $10.67B | $12.21B | $15.46B | +45% YoY |
| CapEx | -$3.79B | -$4.59B | -$5.59B | Expanding capacity |
| Free Cash Flow (FCF) | $9.31B | $10.28B | $12.97B | Healthy & growing |
| Dividends Paid | -$4.50B | -$4.63B | -$4.99B | Stable |
| Net Change in Cash | -$347M | -$208M | $3.65B | Positive reversal |
Strategic Notes:
- Strong commitment to R&D and long-term infrastructure.
- FCF covers dividend with room to spare.
- Net cash build-up confirms strong underlying operations.
Financial Structure & Valuation
| Metric | Value | Interpretation |
|---|---|---|
| Price / Earnings (P/E) | 30.61x | Slightly elevated |
| Price / FCF | 30.01x | Not cheap, not overpriced |
| Price / Sales (P/S) | 4.12x | In line with industry |
| Market Cap | $288B | Large-cap stability |
| FCF Yield | ~3.3% | Stronger than average |
AstraZeneca deserves a mild valuation premium due to consistent growth and superior cash flow, but is not cheap by traditional value metrics.
Price Target Scenarios
| Time Horizon | Price Target | Scenario Description | Upside vs $92 |
|---|---|---|---|
| S1 2026 | $75 | Technical correction, macro + FX pressures | -18% |
| End of 2026 | $90–$95 | Flat to slight recovery, EPS growth priced in | ±0% |
| 2027–2028 | $105–$115 | Pipeline wins + regulatory approvals | +15–25% |
Key Risks
| Risk Type | Level | Explanation |
|---|---|---|
| R&D Dependence | Medium | Pipeline concentration risk |
| Drug Pricing Regulation | High | Potential margin compression in EU/US |
| Currency Volatility | Medium | GBP/USD exposure due to global ops |
| Debt from Acquisitions | Medium | Still manageable under FCF discipline |
| Valuation Compression | Light | May lag if rates stay elevated |
Final Verdict & Recommendation
| Factor | Rating |
|---|---|
| Growth | Strong |
| Profitability | Excellent |
| Free Cash Flow | Record high |
| Dividend / Capital Return | Reliable |
| Valuation | Slightly rich |
| Long-Term Potential | High (>12–18 mo) |
Final Call: HOLD / BUY on Pullback near $75
AstraZeneca is a high-quality, global pharmaceutical cash machine. At $92, the stock is fairly priced, but any pullback toward $75–$80 offers a compelling long-term entry for investors seeking a defensive compounder.
Disclaimer :
This content is for informational purposes only and does not constitute investment advice. All investments carry risk, including the loss of capital. Conduct your own research before making any decision.
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